
Innovatorium 001: Stand 442
Provital
Intensilk™
Intensilk™ is the first cosmetic active to mimic caloric restriction in adipocytes.
Coming from locally sourced apple blossom, Intensilk™ remasters longevity science to dermohack the body for an intensive cellulite treatment with a comprehensive remodeling action on both fat reduction and tissue architecture.
A multi-omic analysis reveals its ability to reprogram adipocyte metabolism from lipid storage to recycling by triggering caloric restriction pathways (PI3K–Akt–mTOR modulation) and activating lipophagy to return energy back to the skin.
Backed by advanced in vitro and in vivo research, Intensilk™ targets all key physiological factors in cellulite development:
• Remodeling tissue architecture by acting simultaneously on lipophagy, adipogenesis, lipolysis, inflammation, while remodeling dermal and hypodermal extracellular matrix.
• Reducing “orange peel” appearance by decreasing lipid accumulation, smoothing dimples, restoring firmness, and achieving even greater efficacy when combined with mechanical massages.
Bridging these benefits, Intensilk™ offers a longevity-driven approach against cellulite appearance for a healthier, more youthful skin texture.




